Iowa State Cyclones vs Baylor Bears Prediction & Preview - 1/7/2026

Updated January 7, 2026


Updated January 7, 2026

The Big 12 has a huge game coming up in Waco on Wednesday night as the unbeaten Iowa State Cyclones take on the Baylor Bears. Iowa State enters this game off to a historic start and with one of the most efficient offenses in the country, while Baylor aims to rebound after a tough outing in its league opener against TCU. Before the action begins in Texas, you can keep reading to get my thoughts on this game, including my Iowa State vs Baylor prediction.
Pick: | Iowa State -4.5 |
Confidence: | 3/5 |
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Score Projection: Iowa State 83 – Baylor 75
Win Probability: Iowa State 71%, Baylor 29%
Iowa State should have the upper hand in this matchup with the Baylor Bears in Waco. Iowa State has already proven it can win against elite teams on the road, even if it has only had to do so one time this season. Expect the combination of elite offense and defense from the Cyclones to help them get a win in this marquee matchup on Wednesday night.
Jay Sanin is the GM and Head of Sports at ATS.io. He has been writing about sports gambling since 2013, handicapping tens of thousands of sporting events. He plays sides and totals aggressively across most sports and is more selective in player prop markets. He does his own modeling across most sports, and his family is jealous of how much time he spends on his precious spreadsheets.
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